Just a thought, I find the characters to be fun and diverse but when you settle down on one it’d be great to either have a choice for one of two weapons/attacks, or have the choice be an unlock for higher/max levels of mastery.
The reason I feel this would be beneficial is that most players will want to end up focusing on a small group of their favourite characters, and adding an alternative weapon/attack would give you much more diversity and let you specialise for what you want most on a per-mission basis.
Some characters wouldn’t make sense to get a different weapon (or would need serious remodelling to accommodate it), so some of them might just get an alternate attack, either LMB or RMB (or potentially both). Obviously, appropriate augments/mutations involving that weapon/attack would need to change too.
Just a few examples/ideas of potential weapon alternatives:
Montana: Flamethrower. Would sacrifice some of his range for higher damage in close range
Miko: Spore clouds. Small, medium speed semi-homing clouds that deal DoT and linger
Toby: Repeater cannon. Replaces charge-up with heat build-up, and provides lower damage with much faster fire rate.
Kelvin: Ice shards. Replaces LMB claws with slightly-arcing thrown icicles. Maybe chargeable to throw a larger icy spear
Orendi: Shadow spin. Replaces RMB with a radial shadow-magic attack, hitting in a fairly close-range AoE
Just some ideas. Not saying this sort of system would be necessary by any means, but it has the potential to add a lot more depth to the game