At this point there are only two things I know of that can “reliably” deal with in game issues on the Xbox, as a user. These are my observations as a second wave Xbox Live beta tester, an Xbox Ambassador, a member of the Insiders Xbox Alpha Ring, and a seventeen+ year veteran of Xbox Live.
Hard restart your console.
It’s simple, safe, and clears your local cache files. It can frequently resolve issues you might be experiencing with a game. This is not a hard reset where you restore your console to the factory defaults. Only perform a hard reset if you are instructed to by an appropriate tech support person, or if you really enjoy that brand new out of the box feeling.
Delete your local game save file.
Do NOT delete all saves! If you delete both the cloud and local save file at once you will kill all your characters, progress, items, everything for that game. I’ve yet to encounter a situation where this helps with Borderlands 3. I include it because it is a common “first line” solution for many games.
Fully power cycling your console clears the local cache and will resolve many problems. (Turning the machine off and back on does not clear the local cache.) On some occasions, corruption can occur in a local save file but it’s not as common as having issues with your local cache, for Borderlands 3. If you have concerns about your ability to do either please check Microsoft’s site on how to perform a hard restart, or how to manage game saves. The two steps listed here will resolve many issues, but not all. It is advisable to reach out to appropriate parties for technical support for issues that are persistent.
Here is a link providing simple instructions from another source on how to hard restart your console.
A quick disclaimer: I am not employed by Microsoft, 2K, or Gearbox. This post is simply sharing my experiences. I wouldn’t share any information I believe could be harmful, but any actions you take are your own responsibility. 