Happens shortly after zoning in the Devil’s Razor during the quest “Blood Drive” its happened to me on 2 characters now with each crashing multiple times (one got through after 4 tries, not sure how it just didn’t crash that time). After the 2nd group of skags attempting to move any further into the zone causes a video driver crash which then requires a full PC restart.
AMD Radeon RX 5700 XT
20.9.1 (most recent available)
**Found the work around (not fix, just work around) changing to DX11 let me get through Devil’s Razor portion of the question. For anyone else who sees this.