Game crashes every time during sanctuary cut scene after Lilith loses powers

I have tried playing with the video settings such as fullscreen, trying directx 12, etc. Need help. Can’t play the game

Bottom line up front, go to “graphics settings.” Change it from “fullscreen” to to “windows” or “windowed borderless” mode. Worked for me. I’m running an NVidia card with Windows 10. And by the way, the latest NVidia driver is a bit gimpy.

Had the same problem… Couldn’t play the game… Following this video tips Helped