Good lord, I hope Jack comes back. He is still, by far, the best Borderlands Bad Guy (second perhaps only to Dr. Ned, who was just comically over-the-top obvious while still trying to act like nothing was wrong). Jack’s character had Charisma and Intelligence, even if he was evil. So while you weren’t rooting for Jack in BL2, you didn’t mind listening to him. In a way, he represented what an aspiring Vault Hunter would do if given half the chance at real power, and that made him relatable.
Jack provided a much needed campaign driver, along with occasional comic relief in the absurdity of his rants. In TPS, we got to see how he ended up the way he did and for a time were rooting for him as he tried to stop the destruction of Elpis (an arguably heroic goal), again demonstrating his likeability. In BL3’s first DLC, we got to feel Jack’s presence and influence again, as well as view an alternate (reality) version through Timothy who gave us an idea of what a more humane Jack might be like.
Jack may have been a [insert derogatory descriptor here], but he had a real, recognizable purpose to his actions that matched the established corporate greed-driven motivations in BL1 that impact the whole of the Borderlands. The Twins, conversely, came across as one-joke, FU’s towards the concept of stereotypical Millennial entitlement. Jack might have been just as narcissistic and ego-centric as either of the Twins, but he EARNED his power the hard way, fighting and clawing his way to the top (just like a VH earns his/her way to Badassery). There is a certain amount of respect that Jack commanded as a result of that, even if you hated him.
Will Handsome Jack ever come back? Doubtful, given what we have heard so far regarding the topic from GB itself. But all that would be needed is a real, workable clone (as opposed to say, Jackenstein), one that he himself setup as a contingency plan ahead of time. Of course, given the destruction of the Hyperion headquarters, it is unclear what all Jack could do once he did return.
Honestly, as much as I (obviously) like the character, if there is too much Jack, then Borderlands becomes the “Kill Jack Show” and that is too restrictive. Still, the franchise needs another compelling charismatic nemesis for the Vault Hunters to go up against, one that you can partially or at least almost sympathize with and one that definitely commands respect. My thought is to leverage one of the existing Vault Hunters like maybe Axton who has gone rogue without the VHs knowing and who is driving them to do his/her dirty work in a bid for power. Then the second half of the storyline could be about fixing the mess that the VHs made in the first half. Just a thought.
In the meantime, I want to see Ava discover a way to bring back Maya through the use of that Siren book and a series of quests (and hopefully sacrifice herself in the process…).