Mouse clicks in menus inconsistent?

I can still shoot just fine, but navigating any menu I’ve found that I often have to double click on things or just use E and other keyboard controls. Especially annoying is having to double click on something and it somehow counts it as two clicks despite not registering a single click (accidentally taking two guns from the bank, for example).
In game, main menu, since the last update (or dlc3, not sure) I’ve been having trouble with this.

This is the Steam version, if that matters.

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I’ve always had this issue as well. Menus (especially in-game) are extremely unresponsive to mouse input but work perfectly with the keyboard. It’s very frustrating.