I would talk about Pheobe or El Dragon with this in mind. If you can’t reach end game because they are dragging you down then what’s the point of having them? About 80 percent of my Advanced modes end in the first 10 minutes of the game.
That said it also depends on how many people you have. I don’t think either of those champions could survive with a five man group. At least I’ve never seen it.
I only put Ambra there because I’ve literally never picked her without someone saying “ugh, Ambra”
I still just prefer Reyna and Alani as healers on most advanced missions because of the increased offensive potential via scoring critical hits more easily and the fact their healing comes in bursts as opposed to ticks. Miko has very strong tick-healing, and its crit damage is very nice, so I feel it is a good choice too.