I just completed The Heliophage three times in a row and for the first two I didn’t even get to loot Rendain because the loot shot out of him in the opposite direction to me, so the 3-5 seconds you’re given before being teleported back wasn’t enough time to reach it.
I recall a similar possibility if you kill ISIC while he’s at a high altitude, where the round can finish before the loot/score even reaches the ground.
