Depends on the weapons … and what one considers troublesome.
There some boss fights where I just did not have ideal weapons, which kept me in the fights too long for her lack of healing skills.
I had to go farm some lvls and weapons for the Sentinel in NVHM, but got through fine in TVHM.
The rest of this is UVHM results…
I did my playthough with found weapons only … not ones I had stored on other characters. Except Deadlift, which I need to borrow a Longnail from one of my other chars to take him out. So, Deadlift was troublesome, as I had hit a wall.
Went down a couple of times against the Bosun. Got down with no 2nd winds nearby.
Rampant Felicity was the other boss I had only green weapons for. That took way too long.
Zarpedon was starting to be problem, until I … dunno … got a good run or something … it was quick and she went down.
I was worried about RK5 as my weapons were not great, but using the jumppads got me through that without any problems.
The Sentinel was hard on the first phase, but finally got 2nd winds when I needed 'em … The other 3 phases seemed easier than NVHM or TVHM.
DId not do the raid boss … yet.