Vehicles in TVHM need a boost to health. In the first playthrough they are perfect in terms of how much damage they can take. Against other vehicles they are 100% even, shot for shot. It’s up to you to shoot better than the enemy. Against NPC’s on the ground you have the advantage as you are in an armoured vehicle with powerful guns which makes total sense but they aren’t hugely OP.
In TVHM, and especially if you go to Mayhem mode not only are you weaker than every other vehicle pound for pound, you can be destroyed in seconds by virtually any NPC on the ground. This is the most obvious when you try and steal a vehicle from NPC’s and they both end up on the ground and instantly begin shooting at you. You’ll be lucky if you can even get 10ft before your vehicle blows up. I understand TVHM is meant to be more challenging but this needs adjustment, especially in the sections of the game where you have to drive as part of the story. There is a certain section of the game where you are forced to use a specific vehicle whose weapons are so utterly weak compared to the numerous vehicles and NPCs you need to fight on the route I got blown up 4 times trying to complete the section. There was nothing I could do about it. I was driving at top speed and shooting everything with solid accuracy.
It needs balancing.