I use Jakobs weapons on my Nisha. My main gun is the Luck Cannon, but I also use the Flayer, Hammer Buster II, Striker, Maggie, blue or purple Coach Guns, and Gatling Guns. Here is the base build that I use with mainly a Celestial Lawbringer, blue High-Rolling Crapshooter, or Six-Shooter COM. Generic, you say? Yes, I know that I am boring.
I find that I have little to no trouble with survivability, and I deal tons of damage with this build. I did not have too much trouble taking down EOS with the dual Luck Cannons.
I was wondering which skill I should take to get to OFEOY. Should I put 5 points in Saddle Up, or Hell’s Coming With Me? Which skill adds more DPS, the extra gun damage of Saddle Up, or the extra fire rate with Hell’s for Jakobs weaponry?