Weird audio bug/glitch. I think

So, I’ve replaced both my controller and my headset and the problem is persisting. It only occurs when BL3 is running, be it actively or in the background. The audio comes through fine on my tv, but the audio will constantly cut out completely to my headphones. The only way to undo this problem is to unplug, wait a moment, then plug back in the headset, which (if I’m lucky) gives me another minute of audio, before it cuts out again.
Again, I’ve changed both my controller and my headset and it only occurs when playong BL3.