Modded items can take a toll on stability. If you see people with modded items on PS4 generally you will experience lag even in single player and other bugs. On PC this is less of an issue if your running the game on a gaming rig designed for optimal performance.
One thing Gearbox did in the past which you may or may not have been around for what nurf to several special bonus projectile weapons like the Cutsman, Hyperfocus, and several others all to improve performance when these guns are being used.
Personally I don’t understand why they don’t scale back the light bloom effects, redice partical effects intensity, and scale back the animations used for status effects on enemies and so on.
I also wouldn’t look at it as na excuse it is more of a justification for cutting corners
Personally I think if a red text legendary like say the Sixth Sense dosn’t work with anointments you should just not put it in the game if the end game is balanced around anointments. I think most of the community has made it clear they only care about the end game experience and not the leveling experience (which is a shame because I have the most fun leveling)